The central research focus of the LSBG is to understand genome organization, regulation, and variation and is broadly partitioned according to three major research pillars:
The Deplancke Lab was recently awarded a Swiss Cancer League Grant, a PHRT Technology Grant, a Jebsen Foundation Grant on Metabolism, an AnimalFreeResearch Grant, an interdisciplinary PhD fellowship grant from the EPFL, as well as a Chan Zuckerberg Foundation Grant.
ASAP: a Web-based platform for the analysis and inter-active visualization of single-cell RNA-seq data (Gardeux et al. Bioinformatics, 2017)
Gene- or transcript-specific primer design for real-time PCR (Gubelmann et al., Database, 2012)
Primer-initiated de novo sequence synthesis for clone identification (cDNA screens), validation, and genomic annotation (indels) (Massouras et al., Nature Methods, 2010)
Detection of amplification-biased sites in allele-specific analysis of ChIP-seq data (Waszak et al., Bioinformatics, 2014)
"Transcription factor-DNA Interaction Detection in Yeast". Software to detect positive interactions in 384-well format in yeast one- and two-hybrid screens (Hens et al., Nature Methods, 2011)